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Diabetic Emergencies: First Aid for Hypoglycemia, DKA, and HHS (2026)

The three primary diabetic emergencies are hypoglycemia (low blood sugar), diabetic ketoacidosis (DKA), and hyperosmolar hyperglycemic state (HHS). For a conscious person with low blood sugar, give 15 grams of fast-acting sugar and wait 15 minutes. That is the Rule of 15. For DKA or HHS, call 911 immediately and do not give food or drink if the person is vomiting or unconscious. If the person is unconscious and carries a glucagon kit, administer it after calling 911.

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World Diabetes Day and Diabetic Emergencies: Why First Aid Matters

Every year on November 14th, the global community observes World Diabetes Day to raise awareness about one of the fastest-growing health conditions in the world. In Canada alone, more than 3.7 million people are living with diabetes, and that number continues to rise every year. While diabetes is primarily managed through lifestyle modifications and medical treatment, the condition can produce life-threatening emergencies that require immediate attention. Diabetic emergencies are critical situations in diabetes management that require immediate attention because they can be life-threatening.

World Diabetes Day was established in 1991 by the International Diabetes Federation and the World Health Organization. November 14th was chosen because it marks the birthday of Sir Frederick Banting, the Canadian physician who co-discovered insulin in 1921 at the University of Toronto. That breakthrough has saved millions of lives and remains one of Canada’s greatest contributions to global health.

The three primary diabetic emergencies are hypoglycemia (low blood sugar), diabetic ketoacidosis (DKA), and hyperosmolar hyperglycemic state (HHS). The two most common diabetic emergencies are diabetic ketoacidosis (DKA) and hyperosmolar hyperglycemic state (HHS), with severe hypoglycemia also being a key concern. Each requires a different first aid response, and each can be fatal without prompt action.

Types of Diabetes: What You Need to Know

Type 1 Diabetes

Type 1 diabetes is an autoimmune condition in which the body’s immune system attacks and destroys the insulin-producing cells in the pancreas. Without insulin, the body cannot move glucose from the bloodstream into cells for energy. People with Type 1 diabetes must take insulin every day to survive. DKA is most common in type 1 diabetes because the absolute shortage of insulin causes the body to produce ketones as an alternative fuel source. This type accounts for approximately 5 to 10 percent of all diabetes cases and is most commonly diagnosed in children and young adults.

Type 2 Diabetes

Type 2 diabetes is the most common form, accounting for about 90 percent of all cases. It develops when the body becomes resistant to insulin or when the pancreas gradually loses its ability to produce enough insulin. HHS is more often seen in people living with type 2 diabetes, although either condition can affect anyone with diabetes. Risk factors include family history, obesity, physical inactivity, age, and ethnicity. Regular monitoring of blood glucose levels is essential for people with diabetes, especially during periods of illness, to prevent fluctuations that can lead to emergencies.

Gestational Diabetes

Gestational diabetes develops during pregnancy and typically resolves after birth. However, women who have had gestational diabetes have a significantly higher risk of developing Type 2 diabetes later in life. Monitoring blood glucose carefully during pregnancy is essential for the health of both mother and baby, and gestational diabetes is considered a risk factor for future hyperglycemic emergencies.

The Three Primary Diabetic Emergencies

What Is Hypoglycemia: Low Blood Sugar and Its Risks?

Hypoglycemia occurs when blood glucose drops below normal levels, which can starve the brain of fuel. In clinical terms, hypoglycemia is defined as blood glucose falling below 4.0 mmol/L. This is the more common and more immediately dangerous diabetic emergency in day-to-day life. It can develop rapidly within minutes and can quickly progress to unconsciousness and seizures if not treated.

Causes of hypoglycemia include taking too much insulin, skipping meals, excessive physical activity, and alcohol consumption. Certain drugs affecting blood glucose control, including medications used for infection or other conditions, can also trigger hypoglycemic episodes. People with hypoglycemia unawareness are at particular risk because they do not experience the usual warning signs before their blood glucose drops to a dangerous level, making bystander recognition even more critical.

Early signs of hypoglycemia include: shakiness and trembling, sweating and pale clammy skin, rapid heartbeat and extreme hunger, dizziness and lightheadedness, confusion and difficulty concentrating, irritability or sudden mood changes, and blurred vision and weakness.

Severe Hypoglycemia: When Low Blood Sugar Becomes Life-Threatening

Severe hypoglycemia can result in seizures, loss of consciousness, or coma. In Ontario, in-hospital mortality in people hospitalized for acute hyperglycemia ranged from under 1 percent at ages 20 to 49 years to 16 percent in those over 75 years, underscoring the importance of early intervention. Severe hypoglycemia requires immediate attention and emergency services if the person is unconscious, having seizures, or unable to swallow safely. The incidence of severe hypoglycemic events increases significantly in older adults and in patients with long-standing diabetes who have developed hypoglycemia unawareness.

What Is Diabetic Ketoacidosis (DKA)?

DKA is a metabolic crisis caused by an absolute shortage of insulin, leading the body to produce ketones as an alternative fuel source. When insulin is absent, the body breaks down fat, producing ketones that acidify the blood. This process is called ketosis and, when severe, progresses to ketoacidosis. DKA is most common in people with type 1 diabetes but can affect anyone with diabetes who has severely uncontrolled blood glucose. Severe diabetic ketoacidosis is a life-threatening hyperglycemic crisis requiring emergency room treatment without delay.

In DKA, blood glucose levels are usually 14.0 mmol/L or above. Symptoms of diabetic ketoacidosis (DKA) include nausea, vomiting, abdominal pain, and a feeling of being unable to get enough oxygen, collectively referred to as acidosis. Common signs of DKA also include shortness of breath, fruity breath odor, and severe abdominal pain. Common triggers for DKA beyond missed insulin include infection, illness, cardiac surgery, and myocardial infarction, all of which dramatically increase the body’s insulin requirements. People recovering from surgery or a cardiac event should monitor blood glucose closely for signs of hyperglycemic crises.

  • Excessive thirst and frequent urination
  • Nausea, vomiting, and severe abdominal pain
  • Fruity breath odor from ketones in the urine and breath
  • Deep and rapid breathing (Kussmaul breathing)
  • Confusion and drowsiness
  • Eventual loss of consciousness and coma

What Is Hyperosmolar Hyperglycemic Syndrome (HHS)?

Hyperosmolar hyperglycemic syndrome (HHS), also called hyperosmolar hyperglycemic state, hyperglycemic hyperosmolar state, or hyperosmolar nonketotic coma, is a hyperglycemic emergency that typically affects older adults with type 2 diabetes. Hyperglycemia usually develops slowly and can lead to severe dehydration and life-threatening conditions like DKA or HHS if untreated. Medications including diuretics and glucocorticoids can trigger or worsen HHS by promoting dehydration and raising blood glucose levels.

In DKA, blood glucose levels are usually 14.0 mmol/L or above, while in HHS they can be significantly higher, typically 34.0 mmol/L or above, along with plasma osmolality above 320 mOsm/kg. HHS typically presents with neurological signs such as vision problems or delirium, along with increased urination and dehydration. Signs of dehydration in HHS include extreme thirst, dry mouth, sunken eyes, and rapid pulse. HHS is a critical medical emergency requiring intensive care treatment and massive fluid rehydration as a priority. Mortality is significantly higher in HHS than in DKA, particularly in older adults and patients with pre-existing conditions.

Safety Tip: If you are unsure whether someone is experiencing high or low blood sugar, always treat for low blood sugar first by giving them something sweet to eat or drink if they are conscious and able to swallow. Treating for low blood sugar when it is actually high causes minimal harm. Failing to treat dangerously low blood sugar can be fatal.

DKA vs HHS: Key Differences at a Glance

Understanding the difference between DKA and HHS helps you communicate more clearly with emergency dispatchers and medical professionals when someone experiences a hyperglycemic crisis.

Feature DKA HHS
Most common in Type 1 diabetes Type 2 diabetes
Blood glucose 14.0 mmol/L or above 34.0 mmol/L or above
Plasma osmolality Normal or mildly elevated Above 320 mOsm/kg
Ketones present Yes Minimal or absent
Onset Hours to 1 day Days to weeks
Breath odor Fruity No fruity odor
Neurological signs Less common Vision problems, delirium common
Dehydration Moderate Severe
Common triggers Missed insulin, infection, cardiac surgery Diuretics, glucocorticoids, illness
Treatment priority Insulin and IV fluids Massive fluid rehydration

First Aid for Diabetic Emergencies: Step by Step

In a diabetic emergency, assessing the person’s level of consciousness and their ability to swallow safely is the most critical first step. Never give anything by mouth to someone who is unconscious or unable to swallow, as this creates a serious aspiration risk. Intermediate / Standard First Aid with CPR C covers diabetic emergency response, the Rule of 15, and glucagon administration as part of the core curriculum.

The Rule of 15: First Aid for Low Blood Sugar

If blood sugar levels cannot be determined, standard protocols suggest treating as if the person has hypoglycemia. This is the safer approach because treating a high blood sugar with a small amount of sugar causes minimal harm, while failing to treat dangerously low blood sugar can be fatal.

For a conscious person who can swallow safely, follow the Rule of 15:

  • Step 1: Give 15 grams of fast-acting sugar immediately. Options include 4 glucose tablets, half a cup (125 mL) of fruit juice or regular soft drink, 1 tablespoon of honey or sugar, or 6 to 7 hard candies.
  • Step 2: Wait 15 minutes and reassess symptoms.
  • Step 3: If symptoms have not improved, repeat the 15-gram dose of fast-acting sugar.
  • Step 4: Once symptoms improve, give a more substantial snack containing both carbohydrates and protein to stabilize blood glucose levels and prevent a rebound drop.

If the person is unconscious or unable to swallow safely, do not give anything by mouth. Call 911 immediately. Place the person in the recovery position on their side to protect their airway. If the person carries a glucagon kit and you are trained to use it, administer glucagon as directed. The glucagon kit works by signaling the liver to release stored glucose into the bloodstream, raising blood glucose without requiring oral intake. Stay with the person and monitor their breathing and level of consciousness until emergency services arrive.

First Aid for Hyperglycemic Emergencies: DKA and HHS

Hyperglycemia that has progressed to DKA or HHS requires emergency room treatment and cannot be managed with first aid alone. Management of diabetic ketoacidosis (DKA) and hyperosmolar hyperglycemic state (HHS) includes restoring normal extracellular fluid volume and correcting electrolyte imbalances. Fluid therapy is essential in managing DKA, with initial intravenous normal saline administration recommended at a rate of 500 mL/h for the first four hours, followed by adjustments based on the patient’s condition.

As a bystander, your role is to call 911 immediately if the person is vomiting, has fruity-smelling breath, is breathing abnormally, or is showing signs of altered consciousness. Keep the person comfortable and calm. Place them in the recovery position if unconscious but breathing. Monitor their airway and breathing continuously. Do not give food or drink if they are vomiting or their level of consciousness is reduced. Tell paramedics what you observed, including any known diabetes diagnosis, medications, and the time symptoms began.

Hypoglycemia Unawareness: A Hidden Risk

Hypoglycemia unawareness is a condition in which a person with diabetes no longer experiences the early warning signs of low blood glucose. Over time, the body’s hormonal response to falling blood glucose becomes blunted, particularly in people who have had diabetes for many years or who have experienced frequent hypoglycemic episodes. Blood glucose can drop to dangerous levels without the person feeling any symptoms.

For bystanders and coworkers, hypoglycemia unawareness means that someone with diabetes may appear suddenly confused, unresponsive, or unconscious without warning. This makes it especially important for people around those with diabetes to know the signs of a diabetic emergency, even when the person themselves cannot signal that something is wrong. If someone with known diabetes suddenly appears confused, pale, or unresponsive, treat for hypoglycemia immediately and call 911.

The Glucagon Kit: What It Is and How It Helps

A glucagon kit is an emergency treatment for severe hypoglycemia when the person is unconscious or unable to swallow. Glucagon is a hormone that signals the liver to release stored glucose into the bloodstream. Many people with type 1 diabetes and some with type 2 diabetes carry a glucagon kit as part of their emergency preparedness.

Glucagon kits come in two forms: an injectable kit that requires reconstitution before use, and a nasal spray form that is simpler to administer. If someone collapses from a diabetic emergency and you locate a glucagon kit, call 911 first, then follow the step-by-step instructions on the kit. The correct dose is included in the kit instructions. Most modern glucagon kits are designed to be used by untrained bystanders with clear instructions. After administering glucagon, the person should begin to recover within 10 to 15 minutes. Even if they recover, paramedics should still assess them because blood glucose may drop again without follow-up treatment.

Sick-Day Plan: Preventing Diabetic Emergencies Before They Start

Preventing diabetic emergencies starts with proactive care, including creating a sick-day plan with healthcare providers to manage medications during illness. Illness and infection are among the most common triggers for both DKA and HHS, because physical stress causes blood glucose levels to rise even if the person is not eating. Sick-day management that includes capillary beta-hydroxybutyrate monitoring reduces emergency room visits and hospitalizations in young people with type 1 diabetes.

A comprehensive sick-day plan typically includes instructions for adjusting insulin or oral medication doses during illness, guidance on how frequently to check blood glucose when sick, rules for when to check for ketones in urine or blood, a threshold for when to call a healthcare provider or go to the emergency room, a list of safe foods and fluids to consume when unable to eat normally, and instructions for managing diuretics, glucocorticoids, and other drugs that affect blood glucose during illness. Regular monitoring of blood glucose levels is essential for people with diabetes, especially during periods when ill, to prevent fluctuations that lead to emergencies.

Diabetes in the Workplace

With 3.7 million Canadians living with diabetes, virtually every workplace has employees managing the condition. Employers have both a legal and ethical responsibility to ensure workplaces are safe and supportive for employees with diabetes. This includes allowing employees to monitor their blood sugar and take medications as needed, providing access to food and beverages for managing blood glucose, training designated first aiders to recognize and respond to diabetic emergencies, and including diabetes management in workplace emergency plans.

Investing in workplace first aid training that covers diabetic emergencies ensures that coworkers can respond effectively when someone experiences a blood sugar crisis. For workplaces with higher risk, private group first aid training can be customized to include specific diabetic emergency protocols. This training aligns with CSA Z1210:24 workplace first aid standards.

Diabetes Prevention: Reducing Your Risk

While type 1 diabetes cannot currently be prevented, the risk of developing type 2 diabetes can be significantly reduced through lifestyle modifications. Maintaining a healthy weight, engaging in at least 150 minutes of moderate physical activity per week, eating a balanced diet, limiting consumption of processed foods and sugary drinks, and getting regular health screenings are all proven strategies. The American Diabetes Association recommends a combination of aerobic exercise and resistance training for optimal glycemic control.

Physical activities like swimming are particularly beneficial for diabetes prevention and management because they provide excellent cardiovascular exercise while being gentle on the joints. Regular physical activity improves insulin sensitivity, helps maintain a healthy weight, and reduces stress, all of which contribute to better blood sugar control and overall health.

This World Diabetes Day: Take Action

This World Diabetes Day, consider taking action by learning the signs and symptoms of diabetic emergencies, talking to friends and family members with diabetes about their emergency action plans, ensuring your workplace has trained first aiders, and enrolling in a first aid course that covers medical emergencies including diabetes.

Basic Emergency First Aid covers the fundamentals of recognizing and responding to blood glucose crises. Intermediate / Standard First Aid courses go deeper, covering the Rule of 15, glucagon administration, recognition of DKA and HHS, and when to call 911. Hands-on training builds the confidence and competence to act correctly under pressure when every minute matters.

Key Takeaway

The three primary diabetic emergencies are hypoglycemia, DKA, and HHS. For a conscious person with low blood sugar, use the Rule of 15: give 15 grams of fast-acting sugar and wait 15 minutes. For DKA or HHS, call 911 immediately. Never give food or drink to someone who is unconscious. If a glucagon kit is available and the person is unconscious, call 911 first then administer glucagon. Hands-on first aid training prepares you to respond with confidence to any diabetic emergency.

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Frequently Asked Questions: 2026 Diabetic Emergencies First Aid

Q1: What are the three primary diabetic emergencies?

A: The three primary diabetic emergencies are hypoglycemia (low blood glucose), diabetic ketoacidosis (DKA), and hyperosmolar hyperglycemic state (HHS). The two most common diabetic emergencies are DKA and HHS, with severe hypoglycemia also being a key concern. Each requires a different response. Hypoglycemia is treated with fast-acting sugar for conscious patients. DKA and HHS require emergency room treatment and cannot be managed with first aid alone. In all three cases, calling 911 and monitoring the person’s airway are the most critical bystander actions.

Q2: What is the Rule of 15 for hypoglycemia?

A: The Rule of 15 is the Intermediate / Standard First Aid protocol for conscious hypoglycemia. Give the person 15 grams of fast-acting sugar such as 4 glucose tablets, half a cup of juice, or 1 tablespoon of honey. Wait 15 minutes and reassess. If symptoms have not improved, repeat the dose. Once symptoms resolve, give a more substantial snack to stabilize blood glucose levels. This protocol is covered in Intermediate / Standard First Aid and CPR certification courses.

Q3: What should I do if someone with diabetes loses consciousness?

A: Do not give anything by mouth. Call 911 immediately. Place the person in the recovery position on their side to protect their airway. If they carry a glucagon kit and you are trained to use it, administer glucagon as directed. The glucagon signals the liver to release stored glucose into the bloodstream. Monitor their breathing and level of consciousness continuously until paramedics arrive. Severe hypoglycemia can result in seizures, loss of consciousness, or coma, so acting quickly is essential.

Q4: What is the difference between DKA and HHS?

A: Both are hyperglycemic crises but differ in key ways. In DKA, blood glucose is typically 14.0 mmol/L or above and ketones are present, producing fruity breath and acidosis. In HHS, blood glucose is significantly higher at 34.0 mmol/L or above, along with plasma osmolality above 320 mOsm/kg. Ketones are minimal or absent in HHS. DKA is most common in type 1 diabetes and develops over hours. HHS typically affects older adults with type 2 diabetes, develops over days to weeks, and presents with severe dehydration and neurological signs. HHS requires massive fluid rehydration as a priority.

Q5: How do I know if someone needs 911 for a diabetic emergency?

A: Call 911 immediately if the person is unconscious or unresponsive, having seizures, unable to swallow, vomiting, breathing abnormally, showing signs of severe dehydration, or has fruity-smelling breath indicating possible DKA. Also call 911 if they do not improve after two rounds of the Rule of 15, or if you are unsure of the cause of their altered consciousness. Diabetic emergencies are critical situations in diabetes management that require immediate attention.

Q6: What is hypoglycemia unawareness?

A: Hypoglycemia unawareness is a condition in which a person with diabetes no longer experiences the early warning signs of low blood glucose. Blood glucose can drop to dangerous levels without the person feeling any symptoms. This makes bystander recognition critical. If someone with known diabetes suddenly appears confused, pale, or unresponsive without warning, treat for hypoglycemia immediately and call 911. People with hypoglycemia unawareness are at significantly higher risk of severe hypoglycemic episodes.

Q7: What is a glucagon kit and who should have one?

A: A glucagon kit is an emergency treatment for severe hypoglycemia in unconscious patients. Glucagon signals the liver to release stored glucose into the bloodstream, raising blood glucose without requiring the person to eat or drink. Many people with type 1 diabetes carry a glucagon kit as part of their emergency preparedness. Glucagon kits are available as injectable preparations or nasal sprays. Call 911 first, then administer glucagon according to the kit instructions at the correct dose. Even if the person recovers after glucagon, they still need paramedic assessment.

More FAQs: DKA, Sick-Day Plans, and Workplace Safety

Q8: What causes DKA and how is it treated?

A: DKA is a metabolic crisis caused by an absolute shortage of insulin, leading the body to produce ketones. Common triggers include missed insulin doses, illness or infection, cardiac surgery, and myocardial infarction. DKA symptoms include nausea, vomiting, abdominal pain, fruity breath, and deep rapid breathing. Treatment requires hospital care including fluid therapy, with initial intravenous normal saline at 500 mL/h for the first four hours, along with insulin and electrolyte correction. As a bystander, call 911 and monitor the person’s airway until help arrives.

Q9: What is HHS and why is it dangerous?

A: Hyperosmolar hyperglycemic syndrome (HHS), also called hyperglycemic hyperosmolar state or hyperosmolar nonketotic coma, is a life-threatening hyperglycemic emergency most common in older adults with type 2 diabetes. Blood glucose rises to 34.0 mmol/L or above, and severe dehydration causes plasma osmolality to exceed 320 mOsm/kg. HHS typically presents with neurological signs such as vision problems or delirium, along with increased urination and extreme thirst. HHS is a critical medical emergency requiring intensive care treatment and massive fluid rehydration as a priority.

Q10: What is a sick-day plan for diabetes?

A: A sick-day plan is a personalized protocol created with a healthcare provider that guides a person with diabetes through managing their condition during illness. It includes instructions for adjusting medications including diuretics and glucocorticoids, monitoring blood glucose more frequently, checking for ketones in urine, and knowing when to seek emergency care. Preventing diabetic emergencies starts with proactive care, including creating a sick-day plan. Sick-day management that includes capillary beta-hydroxybutyrate monitoring reduces emergency room visits and hospitalizations in young people.

Q11: What should I give someone having a hypoglycemic episode?

A: Give 15 grams of fast-acting sugar. Options include 4 glucose tablets, half a cup of fruit juice or regular soft drink, 1 tablespoon of honey or sugar, or 6 to 7 hard candies. Only give food or drink if the person is conscious and able to swallow safely. If blood sugar levels cannot be determined, standard protocols suggest treating as if the person has hypoglycemia. After symptoms improve, follow with a snack containing carbohydrates and protein to stabilize blood glucose.

Q12: How do I recognize DKA symptoms?

A: Common signs of DKA include shortness of breath, fruity breath odor, nausea, vomiting, and severe abdominal pain. Symptoms of diabetic ketoacidosis include a feeling of being unable to get enough oxygen, referred to as acidosis. Blood glucose in DKA is typically 14.0 mmol/L or above, and ketones will be present in urine. The person may also show confusion, drowsiness, and eventual loss of consciousness or coma. DKA symptoms develop over hours to a day, unlike hypoglycemia which can develop within minutes.

Q13: Can diabetes emergencies happen at work?

A: Yes. With 3.7 million Canadians living with diabetes, virtually every workplace has employees managing the condition. Diabetic emergencies can occur at any time, including during high-exertion work, periods of illness, or when meals are delayed. Employers are legally and ethically responsible for ensuring workplaces have trained first aiders who can recognize and respond to blood glucose crises. Private group first aid training can be tailored to include diabetic emergency protocols specific to your workplace.

Q14: What is the difference between hypoglycemia and hyperglycemia?

A: Hypoglycemia is low blood glucose, defined as blood glucose falling below 4.0 mmol/L, which can starve the brain of fuel. Early signs include shakiness, sweating, pale and clammy skin, rapid heartbeat, and extreme hunger. Hyperglycemia is high blood glucose in a hyperglycemic state, typically above 11.0 mmol/L, which develops slowly and can progress to DKA or HHS if untreated. If unsure which condition a person is experiencing, treat for hypoglycemia first, as this is the more immediately dangerous condition.

Q15: Where can I learn diabetic emergency first aid in Canada?

A: Coast2Coast First Aid and Aquatics offers Canadian Red Cross certified Intermediate / Standard First Aid and Basic Emergency First Aid courses across more than 30 locations in Ontario, Nova Scotia, Alberta, and California. Both course levels cover diabetic emergencies, blood glucose management, the Rule of 15, and recognizing signs of DKA and HHS. Online blended learning is available for those who want to complete theory at home before attending an in-person skills session.

Legal Disclaimer
The information in this article is for educational and informational purposes only and does not constitute medical advice. In any diabetic emergency, always call 911 or your local emergency number immediately. Coast2Coast First Aid Inc. assumes no liability for any outcomes resulting from the application or misapplication of information in this article. Proper first aid technique should be learned and practised under the supervision of a qualified instructor.

About This Article, Expertise and Sources
Content reviewed by the Coast2Coast First Aid and Aquatics certified instructor team. Diabetic emergency information sourced from the Canadian Red Cross First Aid Guidelines, the CSA Z1210:24 First Aid Training Standard, Diabetes Canada Clinical Practice Guidelines, and the American Diabetes Association Standards of Medical Care in Diabetes 2026. Coast2Coast First Aid Inc. is an active Canadian Red Cross Training Partner. Last reviewed: May 2026. For corrections or additional information, contact in**@*****************cs.com or 1-866-291-9121.

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About the Author

Ashkon has been a certified First Aid and CPR instructor since 2011 and an Instructor Trainer since 2013. He founded Coast2Coast to help students overcome their fears and gain the confidence to save lives.

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